Ngokoluvo lwethu, esona saphulelo se-nootropic Alpha GPC ngo-2021 usetyenziselwa ubuqu yiCofttek Alpha GPC. Eyona nto intle malunga noku kongezwa kukuba yimveliso yemifuno / i-vegan kwaye ke, wonke umntu angayithatha. Okubaluleke ngakumbi kukuba, isongezelelo asiqulathanga ngqolowa, i-gluten, ubisi, iqanda, intlanzi kunye namandongomane. Ke ngoko, kufanelekile ukuba isetyenziselwe abantu abanezigulo zee-aleji. Nangona kunjalo, ukuba unayo nayiphi na imeko esele ikho, kufuneka uthethe nogqirha wakho kuqala. Esi songezelelo sifumene kuphela uphononongo oluqinisekileyo kwaye senza kanye le nto siyenzayo.

Yintoni iAlfa GPC?

I-Alpha GPC okanye i-L-Alpha Glycerlphosphorylcholine okanye uCholine Alfoscerate yicandelo le-choline yendalo efumaneka ngengqondo. Le khompawundi ikhutshwa kwakhona xa i-acid enamafutha ifunyenwe kwisoy kunye nezinye izityalo. Nangona iAlfa GPC ikhona ngokwemvelo, kuxinzelelo lwayo lwendalo kunye nenani, akwanele ukwenza imisebenzi eyenzelwe ukuxhasa. Ke, iAlpha GPC isoloko imiselwe ukuba isetyenziswe ngendlela yokutya ene-alpha GPC eveliswe ngohlobo lwekhemikhali okanye i-enzymatic deacylation ye-phosphatidylcholine-eyityebise isoya phospholipids.

Uphando olwenziwe kwiAlpha GPC kule minyaka luye lwasekwa njenge parasympathomimetic acetylcholine eyandulelayo evuselela inkqubo ye-parasympathetic luvo kwaye ke, iyanceda kunyango lwe-Alzheimer's kunye neendlela ezahlukeneyo zesifo sengqondo esixhalabisayo. I-Alpha GPC yeyona prodrug efanelekileyo kakhulu kwaye ke, izongezo eziqulathe eli qela zisebenza njengomthombo we-choline yokutya. I-Choline sisondlo esibalulekileyo esidinga ukuba umzimba wenze imisebenzi emininzi ebalulekileyo, njengokukhula kweselula kunye nemetabolism. I-Alpha GPC ikwayi-nootropic esebenzayo ekhulisa ukusebenza kwengqondo kwengqondo. Ihlala ichazwa kwizigulana ezindala ezifumana ukwehla kwengqondo. Ukutya kwe-Alpha GPC nako kunokunyusa imveliso yehomoni yokukhula emzimbeni kwaye ngenxa yoko, iimbaleki ezijikeleze umsebenzi zisebenzisa izongezo zeAlpha GPC ukuphucula amandla azo onke.

Kweli nqaku, sixoxa ngezinto eziphambili zeli candelo, kuquka Izibonelelo zeAlpha GPC, umthamo ochanekileyo, okona kulunga kweAlf GPC okwangoku kwintengiso kwaye umntu angawuthenga phi umgubo ngobuninzi.


Kutheni sifuna IAlfa GPC

Kule minyaka imbalwa idlulileyo, abantu baqale ukunikela ingqalelo ngakumbi kwimizimba yabo. Incoko ejikeleze impilo yengqondo iye yaqina kakhulu njengoko ingqondo isebenza njengeziko lolawulo lomzimba wonke kwaye nakuphina ukungasebenzi kakuhle kwengqondo kunokukhokelela kwiziphumo ezibi. I-Choline idlala indima ebalulekileyo ekugcineni impilo yengqondo kunye nokuphucula ukusebenza kwengqondo. Ke, uninzi lwezongezelelo zokutya ngoku kubandakanya iicomputer ezibonelela nge-choline emzimbeni. Enye yezi zinto Alpha GPC.

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Ukusetyenziswa kweAlfa GPC

I-alpha GPC izongezo zisa izibonelelo ezininzi ezinokubakho. Ukuqala, iAlfa GPC yaziwa ngokuba iphucula impilo yengqondo kunye nokusebenza. Ikwenza oko ngokwandisa amanqanaba e-dopamine kunye nomzimba. Izifundo ezininzi ziye zadibanisa eli khompawundi kunye nomsebenzi ophuculweyo wememori kunye namandla okufunda. Kwezinye iimeko ezithile, izongezo ze-alpha GPC zikwazile ukubuyisela imemori nangona iimeko ezinjalo zikude kwaye zimbalwa. Ngaphandle kokuphucula ukusebenza kwengqondo kunye nokuqonda, kukho ubungqina obaneleyo bokungqina ukuba i-Alpha GPC inokusetyenziselwa ukunyanga isifo i-Alzheimer's, iintlobo ezahlukeneyo zesifo sengqondo esixhalabisayo, kunye nokuhlaselwa kweschemic okwethutyana. Ikhompawundi ikwasetyenziswa ziimbaleki njengoko ikhulisa ukusebenza kwazo. Ukuqukumbela, i-alpha GPC inezibonelelo ezininzi ezimiselweyo, into ephambili eyongeze ukuthandwa kwayo kwiminyaka yakutshanje.

Izinzuzo ze-Alpha GPC

Izongezelelo ze-Alpha GPC zifumene ukuthandwa okungathethekiyo ngenxa yesakhono sekhompawundi sokunceda umzimba ukuba uphinde uchache kwiziphene ezininzi. Kule nxalenye, sixoxa ngokusetyenziswa okumiselweyo kweZibonelelo zeAlpha GPC.

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Kuyasebenza ekunyangeni isifo se-Alzheimer's

Ukutyhubela iminyaka kuye kwenziwa izifundo ezininzi ukufundisisa ubuchule beli khompawundi ukunceda kunyango lwe-Alzheimer's. Olunye uphononongo olunje luveze ukuba iAlpha GPC inyusa inqanaba le-acetylcholine kwingqondo. I-Acetylcholine inxulunyaniswa nokusebenza kwengqondo okuphuculweyo kunye nokuphuculwa kokuqonda. Okubaluleke ngakumbi, uphononongo lukwatyhile ukuba kubantu abanexinzelelo, iAlpha GPC inciphise ukudumba okujikeleze imithambo yegazi kwingqondo, ngaloo ndlela ikhokelela ekusebenzeni kwengqondo okuphuculweyo.

Uphando lubonakalisile ukuba abaguli abasokolayo Isifo se-Alzheimer unokufumana inzuzo ngokuthatha i-1200 mg ye-alpha GPC imihla ngemihla. Le dosi iyacetyiswa ixesha elingangeenyanga ezi-3 ukuya kwezi-6 kwaye iphucula kakhulu izakhono zokucinga zabantu abaphethwe sesi sifo sibulalayo.(2). UDoggrell SA kunye noEvans S; Evans (Okthobha 2003).

Inceda ekunyangeni isifo sengqondo esixhalabisayo

Abantu abaninzi bayabhideka phakathi kwesifo sengqondo esixhalabisayo kunye neAlzheimers. Ke, kubalulekile ukumisela umahluko phakathi kwezi zimbini zokuqala. Isifo sengqondo esixhalabisayo ligama eliqhelekileyo elisetyenziselwa ukuchaza ukwehla kwengqondo yomntu ukuya kuthi ga apho ukwehla kuqala ukuphazamisa imisebenzi yemihla ngemihla yomntu. Isifo i-Alzheimer ayisosifo sengqondo esixhalabisayo kodwa sisifo esithile esisesinye sezona zinto zixhaphakileyo kwisifo sengqondo esixhalabisayo.

Kwiminyaka edlulileyo, izifundo ezininzi ziye zenziwa ukufunda ngefuthe lokutya kwe-alpha GPC kwizigulana ezinesifo sengqondo esixhalabisayo. Olunye uphando lubonise ukuba ukuthatha rhoqo i-alpha GPC ngaphezulu kweenyanga ezintandathu kuphuculwe ukuqonda kunye nokusebenza kwizigulana ezinobuthathaka bokuwohloka komqondo. Ngokufanayo, esinye isifundo sidibanisa ukusetyenziswa kwe-alpha GPC eqhelekileyo kunye nokuphuculwa kwengqondo kwizigulana ezinesifo sengqondo esixhalabisayo kunye nesifo secypbrovascular. Ukuqukumbela, abantu abanesifo sengqondo esixhalabisayo banokuxhamla kakhulu ekuthatheni i-1000 mg ye-Alpha GPC kwidosi yemihla ngemihla. Kwizigulana ezinjalo, ukuthathwa kweAlf GPC kudityaniswa nokuziphatha okuphuculweyo, imvakalelo, kunye nengqondo.

Isetyenziselwa ukunyanga ukuhlaselwa okwenzeka okwexeshana

Ukuhlaselwa okwexeshana kwe-ischemic (TIA) zeziqendu ezifutshane zokungasebenzi kakuhle emzimbeni, zihlala zibangelwa kukuphazamiseka ekunikezelweni kwegazi kwingqondo nakwiliso. Uhlaselo lwe-ischemic lwexeshana luhlala luhlala nje imizuzwana embalwa kodwa lubonwa njengangaphambi kokubetha. Isifundo senziwa ukuze kufundwe isiphumo se-Alfa GPC kwisifo sokubetha kunye nezigulana ze-TIA. Olu phando luveze ukuba abantu abathathe i-1200-mg ye-Alpha GPC isithuba semihla engama-28, balandelwa ngu-1200 mg / usuku lwe-Alfa GPC (ngamanyathelo omlomo) kwiinyanga ezintandathu, babonisa izakhono zokucinga ezingcono kunye nokuvuselelwa okungcono kwi-TIA .

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Iyenza iNcediso yeNootropic esebenzayo

I-Acetylcholine yikhemikhali esebenzayo into esebenza njenge-neurotransmitter kwaye ibalulekile kwimemori kunye nasekufundeni imisebenzi. I-Alpha GPC yonyusa le khemikhali ngaphakathi kwengqondo, ngaloo ndlela ikhokelela kwimemori eyaphuculweyo kunye nokuqonda. Ke, i-alpha GPC ihlala isetyenziswa njengecandelo eliphambili kwizongezo zokutya ezenziwa yi-nootropic.

Iphucula ukusebenza kweembaleki

Kwimbaleki, ukungena kwe-alpha GPC kudityaniswa nokunciphisa umzimba okunyanzelise i-choline. Okubaluleke ngakumbi, kunxulunyaniswa nokwanda kokuveliswa kwehomoni kunye nokunyusa umgangatho wokusebenza. Ke, abaqeqeshi kunye nabaqeqeshi bahlala bacebisa iimbaleki ukuba zisebenzise i-alpha GPC ukufezekisa ukuphuculwa kwemisipha.

I-Dosi ye-alfa GPC

Isifundo esenziwe ukuqonda isiphumo se-alpha GPC kwisiphumo sokukhutshwa kwamandla sibonisa ukuba i-dosage ye-600 mg ibangela ukunyuka kokukhuselekileyo kwe-hormone yokukhula. Ke, umgangatho umthamo we-alpha GPC ihlala iphakathi kwama-300 ukuya kuma-600 mg kwaye iimbaleki kucetyiswa ukuba zibambelele kumda ophezulu.

Nangona kunjalo, xa kufikwa kunyango lokwehla kwengqondo, phantse zonke izifundo ezihlalutye isiphumo seAlpha GPC ekusebenzeni kwengqondo zisebenzisa idosi esemgangathweni ye-1200 mg ngosuku, yahlulwe yangamanani amathathu e-400 mg. Ukwehla kwesi sixa semithamo akunakuba neziphumo ezifanayo njenge-1200 mg yedosi ngosuku. Ke, abaguli abanesifo se-Alzheimer's, isifo sengqondo esixhalabisayo, kunye ne-TIA bahlala becetyiswa ukuba babambelele kwi-1200mg / ngosuku yedosi.

Ngaba iAlfa GPC ikhuselekile?

Zonke izifundo ezenziweyo ukuhlalutya iziphumo ezahlukeneyo zeAlf GPC kwimisebenzi eyahlukeneyo yomzimba ziyavuma ukuba ikhemikhali, xa ichithwe ngaphakathi kwemida yayo yemihla ngemihla, ikhuselekile ngokupheleleyo. Nangona kunjalo, ukubambelela kakhulu kwe-Alpha GPC kunokukhokelela kwiziphumo ebezingalindelekanga, ezinjengeentloko ebuhlungu, ukubetha kwentliziyo, ukungalali kunye nesiyezi. Okubaluleke kakhulu, abasetyhini abakhulelweyo nabancancisayo akufuneki basebenzise eli khomputha njengoko kungekho sifundo senziweyo ukuza kuthi ga ngoku sokufunda iziphumo zeAlf GPC kwabasetyhini abakhulelweyo. Ngokukwanjalo, ukuba imeko yakho sele ikho ngaphambili, kungcono ukubonisana nodokotela wakho ngaphambi kokuqala nangasiphi na isongezelelo se-Alfa GPC.

Ungawuthengaphi Powder yeAlpha GPC ngobuninzi?

Ukuba yinkampani eyenza iAlf GPC izongezo okanye umntu oqonda izibonelelo zayo ezininzi kwaye ke, uzinikele kuyo ngokupheleleyo, unokuziva isidingo Thenga umgubo weAlfa GPC ngobuninzi. Izinto zokuxhasa ezikhoyo kwimarike zihlala zikwicala elibizayo kwaye zanele nje ukuhlala iiveki ezimbalwa. Ukuba ufuna ukuthenga i-Alfa GPC ngobuninzi, eyona ndawo ifanelekileyo yokuthenga Cofttek.

ICofttek ngumvelisi ongezelelweyo wezinto zokwakha ongene ezivenkileni ngo-2008 kwaye usekele ubukho bazo kwihlabathi liphela kwiminyaka embalwa. Inkampani izenzele igama ngokusebenzisa iimveliso ezikumgangatho ophezulu. Namhlanje, inkampani ibonelela ngeemveliso kwiinkampani ezenza amayeza eNtshona Melika, eYurophu, eIndiya nase China. I-Alpha GPC ebonelelwe yiCofttek yimveliso ekumgangatho ophezulu ehlala ihleli ngonaphakade. Ke, ukuba ufuna iAlf GPC ngobuninzi, eyona ndawo ifanelekileyo yokuthenga apha:imveliso-28319-77-9 

Inqaku ngu: UGqr. Zeng

Isiqendu ngo:

UGqirha Zeng

Umququzeleli, ubunkokheli bobunkokheli kwinkampani; I-PhD ifunyenwe kwiYunivesithi yaseFudan kwi-organic chemistry. Ngaphezulu kweminyaka esithoba yamava kwi-organic chemistry kunye noyilo lweziyobisi synthesis; phantse i-10 lamaphepha ophando apapashwe kwiijenali ezigunyazisiweyo, nangaphezulu kweepatent ezintlanu zase China

Ucaphulo

(1). I-US National Library of Medicine Iziko leLizwe lezeMpilo, uGatti G, Barzaghi N, Acuto G, Abbiati G, Fossati T, Perucca E., 1992 Sep; 30 (9): 331-5.

(2). UDoggrell SA kunye noEvans S; Evans (Okthobha 2003). "Unyango lwesifo sengqondo esixhalabisayo kunye nokumodareyitha kwe-neurotransuction". Uluvo lweengcali Ukuphanda iziyobisi. I-12 (10): 1633-1654.

(3). UParnetti, uLucilla; okqhubekayo. (2007). "Umanduleli we-Cholinergic kunyango lokuphazamiseka kwengqondo: iindlela ezingasebenziyo okanye isidingo sovavanyo kwakhona?". Ijenali yeeNzululwazi zeNeurological. 257 (1–2): 264–9.

(4). Uhambo lokujonga umz.

(5). I-Oleoylethanolamide (oea) -i-wand yemilingo yobomi bakho.

(6). I-Anandamide vs cbd: yeyiphi engcono kwimpilo yakho? Yonke into ekufuneka uyazi ngabo!

(7). Yonke into ofuna ukuyifumana malunga ne-nicotinamide riboside chloride.

(8). Izongezo zeMagnesium l-threonate: izibonelelo, idosi, kunye neziphumo ebezingalindelekanga.

(9). Palmitoylethanolamide (ertyisi): izibonelelo, idosi, ukusetyenziswa, isongezelelo.

(10). Izibonelelo zezempilo ezi-6 eziphezulu ze-resveratrol supplements.

(11). Izibonelelo ezi-5 eziphezulu zokuthatha i-phosphatidylserine (ps).

(12). Izibonelelo ezi-5 eziphezulu zokuthatha i-pyrroloquinoline quinone (pqq).

(13). Olona nyango lulungileyo lokuguga lwenicotinamide mononucleotide (nmn).