Emva kophononongo luka-2019 kugqityiwe oko Nicotinamide Mononucleotide kukhuselekile ukusetyenziswa kwabantu ukuba ukusetyenziswa kwayo kuthintelwe kumda obekiweyo, iinkampani ezininzi zokuvelisa zingene kwimarike kunye neminikelo yazo. Oku kugqitha kokukhetha kushiye abathengi bedidekile ukuba yeyiphi I-Nictonimade Mononucleotide (NMN) isongezelelo ilungele bona. Ngokoluvo lwethu, olona nyango lulungileyo lokuguga lweNicotinamide Mononucleotide (NMN) kwi2021 yinkampani yaseCofttek.
ICofttek yinkampani ekalwe ngo-A + esele ikwimakethi phantse iminyaka eyi-12 kwaye iphuhlise isiseko somlandeli othembekileyo ngeli xesha. I-NMN powder ebonelelwa yinkampani kuvavanywa iilebhu kathathu, ibanga lamachiza i-NMN ifunyenwe kwiinkampani ezifanayo ezazibonelele nge-NMN kwizilingo ezahlukeneyo zeklinikhi zabantu ezenzekileyo kule minyaka idlulileyo. Inkqubo ye- Umgubo we-NMN ebonelelwa yiCofttek yenza ukuba lula ukungena kwayo emzimbeni, ngaloo ndlela yandisa ukubakho kwemveliso kunye nemisebenzi yayo yomzimba. Eyona nto ibaluleke kakhulu, le powulu iza ngobuninzi kwaye ungayigcina iinyanga ezintathu. Konke kuyo yonke le nto enye yezongezo ezilungileyo ngoku ezikhoyo kwimarike enomgangatho ophezulu womsebenzisi kwaye ivela kwinkampani ehambise iimveliso ezinokuthenjwa nezisebenzayo unyaka nonyaka.

FAQ

Yintoni iNicotinamide Mononucleotide (NMN)?

INicotinamide Mononucleotide (1094-61-7okanye i-NMN yi-nucleotide ekhoyo ngokwendalo kuninzi lokutya esikutyayo. Itholakala kwi-avocado, i-broccoli, ikhukhamba, ikhaphetshu, i-edamame kunye neetumato. Nangona kunjalo, ubungakanani be-NMN ebonelelwa koku kutya akonelanga ukugcina imisebenzi ephambili yomzimba kwaye ke, abantu bahlala becetyiswa ukuba bathathe izongezo ze-NMN. Kodwa, kutheni iNMN ibaluleke kangaka emzimbeni?

INicotinamide Mononucleotide okanye i-NMN sisandulela seNicotinamide Adenine Dinucleotide okanye iNAD +. Ngamazwi alula, i-NMN sisixhobo esiguquka sibe yi-NAD + ngothotho lweempendulo zamachiza ezenzeka ngaphakathi kwiiseli. I-NAD +, kwelinye icala, ithathwa njengebalulekileyo emzimbeni njengoko isenza imisebenzi ephambili, kubandakanya ukulinganisa isingqisho somzimba, ukophula izakhamzimba ukukhupha amandla eselula, kunye nokwenza lula iimpendulo ze-enzymatic, ezinye zazo ezilibazisa ukuguga. Ngelishwa, nangona i-NAD + ifumaneka kwiseli nganye yomzimba, ukuveliswa kwayo kuyancipha ngobudala. Okubaluleke ngakumbi, akukho kutya umntu anokukutya ukwandisa imveliso ye-NAD + emzimbeni. Yiyo loo nto, umzimba ufuna i-NAD + eyandulelayo eguqula ibe yi-NAD + ngaphakathi kweseli, ngaloo ndlela ilungelelanise ukwehla kwayo emzimbeni. Kulapho ukusetyenziswa kwezibonelelo zeNMN kudlala khona.

Yintoni elungileyo yeNmn?

I-NMN ifunyenwe iphucula umsebenzi we-insulin kunye nemveliso, ekhokelela kwizibonelelo ezongezelelekileyo ze-metabolic kunye nokunyamezelana kweswekile. Ngokukodwa, izongezo ze-NMN zinokunceda ukusebenza ukunciphisa imeko ye-metabolic enjengesifo seswekile, isifo sesibindi esinamafutha, kunye nokukhuluphala.

Ngaba i-nmn ingaguqula ukwaluphala?

Ulawulo lweNicotinamide mononucleotide (NMN) INicotinamide mononucleotide (NMN) yokuxhasa ikhuthaza iprofayile yokubonisa ukuguga ye-miRNA kwi-aorta yeempuku ezindala, ukuxela kwangaphambili ukuvuselelwa kwe-epigenetic kunye neempembelelo ezichasene ne-atherogenic.

Uyinyusa njani iNmn ngokwendalo?

I-NMN inokunikezelwa ngokukhuselekileyo kwiimpuku kwaye ifunyenwe ngokwendalo kwinani lokutya, kubandakanya ibroccoli, ikhaphetshu, ikhukhamba, i-edamame kunye neavokhado. Isifundo esitsha sibonisa ukuba xa i-NMN inyibilikiswa emanzini okusela kwaye yanikwa iimpuku, ibonakala kwigazi elingaphantsi kwemizuzu emithathu.

Ngaba iNmn ingonyusa ubude bexesha elide?

Izazinzulu zifunde ezimbini eziphakathi, i-nicotinamide riboside (NR) kunye ne-nicotinamide mononucleotide (NMN), ngakumbi kunabanye, kwaye uphando luyakhuthaza. Izifundo ezininzi zibonisa ukuba ukongeza kwezi zinto zandulelayo kunokunyusa amanqanaba e-NAD + kwaye kwandise ixesha lokuphila kwegwele, iintshulube kunye neempuku.

Uhlala ixesha elingakanani kwi-Nmn kwinkqubo yakho?

Isifundo sethu sangoku sibonisa ngokucacileyo ukuba i-NMN ifunxwa ngokukhawuleza ukusuka emathunjini ukuya ekujikelezeni kwegazi ngaphakathi kwe-2-3 min kwaye ikwasuswa ekujikelezeni kwegazi ukuya kwizicubu ngaphakathi kwe-15 min.

Kwenzeka ntoni xa uyeka ukuthatha iNmn?

Zombini iResveratol kunye neNMN zisebenza ngokuphucula amandla eeseli emzimbeni wakho ukuzilungisa. Ke, ukuba ubathatha ithutyana kwaye uyimise ayizukubangela ukuba ubuyele kwangoko kwimeko obukuyo ngaphambi kokuba ubathathe kuba utshintsho lolona phuculo lwenziweyo kwiseli.

Ngaba iNmn ikwenza ubonakale umncinci?

"Ilebhu yethu ibonakalise ukuba ukunika i-NMN iimpuku ngaphezulu kweenyanga ezili-12 kubonisa iimpembelelo zokulwa ukwaluphala." Ngokuka-Imai, ukuguqulela iziphumo ebantwini kubonisa ukuba i-NMN inokubonelela umntu ngemetabolism yeminyaka eli-10 ukuya kwengama-20 emncinci.

Leliphi elona nyathelo lilungileyo lolusu eligugileyo?

Izixhobo ezili-12 eziLungileyo zokuLwa nokuGuga

  • Curcumin
  • EGCG
  • Collagen
  • CoQ10
  • I-Nicotinamide riboside kunye ne-nicotinamide mononucleotide
  • Crocin
  • Intetho yesibongo, imvelaphi, ukuhambelana kwefayili Theanine
  • Rhodiola
  • Garlic
  • Astragalus
  • Fisetin
  • Resveratrol

Ndingayiguqula njani imibimbi ngokwendalo?

  • Nxiba ilanga.
  • Nciphisa ukutya iswekile.
  • Yeka ukutshaya.
  • Sebenzisa ioyile yekhokhonathi.
  • Thatha i-beta carotene.
  • Sela iti yelamuni yamagqabi yebhalsam.
  • Guqula indawo yokulala.
  • Hlamba ubuso bakho.
  • Gwema ukukhanya kwe-ultraviolet
  • Nyusa ii-antioxidants zakho

Ndingalujika njani ulusu olugugayo?

Ukunceda abaguli babo bathintele ukwaluphala kolusu ngaphambi kwexesha, iidermatologists zinika abaguli ezi ngcebiso zilandelayo.

  • Khusela ulusu lwakho elangeni yonke imihla.
  • Faka isicelo somsuki we-tanner kunokuba ufumane i-tan.
  • Ukuba uyatshaya, yeka.
  • Kulumkele ukuphindaphinda imbonakalo yobuso.
  • Yitya ukutya okusempilweni, okunesondlo.
  • Sela utywala obuncinci.
  • Zilolonge iintsuku ezininzi zeveki.
  • Coca ulusu lwakho ngobunono.
  • Hlamba ubuso bakho kabini ngemini nasemva kokubila kakhulu.
  • Yeka ukusebenzisa iimveliso zokhathalelo lolusu ezihlabayo okanye ezitshisayo.

Ucebisa ntoni uSinclair?

UDavid Sinclair uthatha:

I-Resveratrol-1g / yonke imihla-ngeentsasa ngeyogathi (jonga apho ungathenga khona) INicotinamide Mononucleotide (NMN) - 1g / yonke imihla - ekuseni (jonga apho ungathenga khona) ebusuku - ngaphandle kweentsuku zokuzilolonga.

Ngaba i-Nmn ineziphumo ebezingalindelekanga?

Xa ithathwa ngomlomo: I-Nicotinamide riboside i-POSSIBLY SAFE xa isetyenziswe ixesha elifutshane. Iziphumo ebezingalindelekanga ze-nicotinamide riboside zihlala zimnene. Iziphumo ebezingalindelekanga zinokubandakanya iingxaki zesisu ezifana nokucaphuka, ukudumba, okanye iingxaki zolusu njengokurhawuzelela nokubila kakhulu.

Ziziphi iziphumo ebezingalindelekanga ze-resveratrol?

Xa ithathwa ngomlomo: I-Resveratrol KUNYE UKHUSELEKILE xa isetyenziswe kwiimali ezifumaneka kukutya. Xa uthathwa ngeedosi ukuya kuthi ga kwi-1500 mg yonke imihla ukuya kuthi ga kwiinyanga ezi-3, i-resveratrol i-POSSIBLY SAFE. Iidosi eziphezulu ukuya kuthi ga kwi-2000-3000 mg yemihla ngemihla zisetyenziswe ngokukhuselekileyo kwiinyanga ezi-2-6. Nangona kunjalo, la maqondo aphezulu e-resveratrol anokubangela iingxaki zesisu.

Ngaba inicotinamide ikhuselekile ukuthatha yonke imihla?

I-Nicotinamide riboside inokukhuseleka kunye neziphumo ebezingalindelekanga ezimbalwa. Kwizifundo zabantu, ukuthatha i-1,000-2,000 mg ngosuku akukho ziphumo zibi. Nangona kunjalo, uninzi lwezifundo zabantu lufutshane ngexesha kwaye bambalwa abathathi-nxaxheba. Ukufumana umbono ochanekileyo wokukhuseleka kwayo, kufuneka kwenziwe izifundo zabantu ezomeleleyo.

Kutheni i-NADH imbi kakhulu?

Le NADH igqithileyo inokuphula ibhalansi ye-redox phakathi kwe-NADH kunye ne-NAD +, kwaye ekugqibeleni ingakhokelela kuxinzelelo lwe-oxidative kunye neendlela ezahlukeneyo ze-syndromes zemetabolic.

Yeyiphi engcono iNmn okanye iNR?

I-NR ihlala icingelwa njengesandulela esisebenza kakuhle kwi-NAD +, kodwa i-molecule yayo yomzala i-NMN, ngelixa ingesiso isithako esisisiseko, iphakamisa amashiya njengomntwana omtsha kwibhloko.

I-NMN inkulu nje kune-NR, oko kuthetha ukuba ihlala ifuna ukwaphulwa ukuze ilingane neseli. I-NR, xa ithelekiswa nezinye i-NAD + zangaphambili (njenge-nicotinic acid okanye i-nicotinamide) ilawula ngokugqwesileyo ekusebenzeni kakuhle. Kodwa nika i-NMN umnyango omtsha, onokungena kuyo, kwaye ngumdlalo omtsha ngokupheleleyo.

Yeyiphi eyona nmn yongezelelekileyo?

  • Yeyiphi eyona nmn yongezelelekileyo?
  • Amacwecwe e-NMN Sublingual Tablets.
  • I-NAD + yeGolide yeLiposomal NMN.
  • Iicapsules zeNMN.

Ngaba i-nmn iguqula ukuguga?

Iindlela zokunyanzela ukonyuka kwamanqanaba e-NAD + zibonisiwe ukuphucula ukusebenza kwe-mitochondrial kwizilwanyana ezindala, kuguqula ezinye zeelahleko ezenzeka kubudala. Ukulawulwa kwe-nicotinamide mononucleotide (i-NMN) kubonisiwe ukunciphisa ukungasebenzi kakuhle okunxulumene nokuguga.

Yimalini ekufuneka uyithathile?

Ngelixa izifundo ziye zafumanisa ukuba iNicotinamide Mononucleotide okanye i-NMN ikhuselekile ekusetyenzisweni komntu, kusaqhutywa uphando ukuze kufunyaniswe owona mthamo kunye nokuhamba rhoqo kweedosi zeNMN ebantwini. Nangona kunjalo, izifundo esele zenziwe ukuza kuthi ga ngoku ziye zafumanisa ukuba idosi efikelela kwi-500 mg ngosuku ikhuselekile emadodeni. Kule mihla, iNicotinamide Mononucleotide ifumaneka ngeendlela ezahlukeneyo, kubandakanya iipilisi kunye nomgubo. Ababoneleli ngeNMN bongeze ukuba izongezo zomlomo zisebenza ngokunyusa imveliso ye-NAD + emzimbeni. La mabango asekwe kwinto yokuba iSlc12a8, i-nicotinamide nucleotide transporter, iyanceda ukufunxwa kwe-NMN emathunjini.

Ngaba iNmn iyafana ne-b3?

I-NMN ayisiyiyo. I-NMN ayilulo uhlobo lwevithamini B3, kwaye azikho izilingo zeklinikhi ukubonisa ukuba iyayonyusa i-NAD ebantwini. I-NMN ayilulo uhlobo lweemolekyuli eziya kuthi zithathelwe ingqalelo njengevithamini njengoko inephosphate, echaphazela amandla ayo okungena kwiiseli.

Kukuphi ukutya okuneyona nto iphambili kwi-NAD +?

Ukutya okuphucula amanqanaba e-NAD

Kukho ukutya okuthile okunokunyusa amanqanaba e-NAD emzimbeni. Ezinye zazo zibandakanya:

  • Ubisi lobisi-Uphando lubonakalisile ukuba ubisi lweenkomo ngumthombo olungileyo weRiboside Nicotinamide (RN). Ilitha yobisi lwenkomo olutsha luqukethe malunga ne-3.9µmol ye-NAD +. Ke ngelixa unandipha iglasi yobisi ehlaziyayo, eneneni uya usiba mncinci kwaye usempilweni!
  • Iintlanzi - nasi esinye isizathu sokuba uyonwabele intlanzi! ezinye iintlobo zeentlanzi ezifana ne-tuna, iisalmon kunye neesardadi yimithombo etyebileyo ye-NAD + yomzimba.
  • Amakhowa-abantu abaninzi bayawathanda amakhowa kunye nabo njengokutya okuqhelekileyo kukutya kwabo kwesiqhelo. Kodwa ubusazi ukuba amakhowa, ngakumbi amakhowe e-crimini, ayanceda ekunyuseni ngokwendalo amanqanaba e-NAD? Ewe kuyinyani. Ke, konwaba ukutya amakhowa kwaye uqhubeke ujongeka kwaye umncinci kwaye ulutsha ngakumbi!
  • Igwele- sisithako esisetyenziselwa ukwenza isonka kunye nezinye iimveliso zokubhaka. Igwele liqulathe iRiboside Nicotinamide (RN), eyandulela i-NAD. Nasi esinye isizathu sokuba ukonwabele ukutya kweebhaki zakho okanye iivenkile zakho nanini na undwendwela indawo ekubhakwa kuyo! Yonwabela ukutya okuthandayo ngelixa ukonyusa amanqanaba e-NAD ngaxeshanye. Kupholile oko!
  • Imifuno eluhlaza - imifuno eluhlaza inazo zonke iintlobo zezakha mzimba eziluncedo ngeendlela ezahlukeneyo. Kutshanje, kuye kwavela ukuba imifuno eluhlaza ikwangumthombo olungileyo we-NAD yomzimba. Eminye yale mifuno ibandakanya i-ertyisi kunye ne-asparagus.
  • Iinkozo ezipheleleyo-njengoko kuchaziwe ngaphambili, iVitamin B3 ikwanayo ne-RN, eyandulela i-NAD. Nangona kunjalo, xa imifuno, izinto zokutya okanye iinkozo ziphekiwe okanye zilungiswa, baphulukana nesondlo kunye nomthombo wevithamini. Ke ngoko kuyacetyiswa ukuba kufuneka utye imifuno eluhlaza kunye nokutya ukutya okuziinkozo endaweni yokutya okwenziweyo.
  • Nciphisa iZiselo ezinxilisayo-i-NAD inoxanduva lokugcina iinkqubo zemetabolism zomzimba. Utywala buthanda ukuphazamisa ezi nkqubo kunye nokunciphisa ukusebenza kwe-NAD. Ke ngoko, kuya kufuneka ukuthintele ukuselela kakhulu iziselo ezinxilisayo kuba nazo azilunganga kwimpilo yakho.

Ngaba iNmn ibangela ukugungxula?

'I-Niacin flush' sisiphumo esisecaleni sokuthatha idosi ephezulu ye-niacin eyongezelelweyo (Vitamin B3). Ukuqhuma kwenzeka xa i-niacin ibangela ukuba ii-capillaries ezincinci kulusu lwakho zide, ezonyusa ukuhamba kwegazi kumphezulu wolusu. Ngokungafaniyo nokufakwa kwi-vitamin B3 (niacin), inicotinamide riboside akufuneki ibangele ukugungxwa ebusweni.

Ndingayithenga phi iNmn eCanada?

I-NMN yi-nucleotide ephuma kwi-ribose kunye ne-nicotinamide. Njenge-nicotinamide riboside (Niagen), i-NMN sisiphumo se-niacin, kunye nomanduleli kwi-NAD +. I-NMN Canada: I-Nicotinamide mononucleotide ayifumaneki okwangoku njengesixhobo sokutya eCanada.

Ngaba iNmn ikhuselekile?

Kule minyaka idlulileyo, kwenziwe izifundo ezininzi zokufunda ukuba ukusetyenziswa kwe-NMN ebantwini kukhuselekile okanye akunjalo. Ezi zifundo ziye, amaxesha ngamaxesha, ziveze ukuba ukusetyenziswa kweNicotinamide Mononucleotide kukhuselekile ngokupheleleyo xa idosi yayo ithintelwe. Ngokubanzi, amadoda ayacetyiswa ukuba anamathele kwidosi yemihla ngemihla engaphantsi kwe-500 mg. Nangona kunjalo, kufuneka kugqitywe ukuba i-FDA ayikamkeli i-NMN njengechiza elikhuselekileyo. Ke, ukuba unayo nayiphi na into yokugula okanye iingxaki zonyango, kungcono ukuba ubonane nogqirha wakho ngaphambi kokuqala naziphi na izongezo ze-NMN.

Yeyiphi engcono i-NAD okanye i-NMN?

I-NAD kunye ne-NMN zizinto ezidumileyo zokuxhasa ukuguga, kwaye ngenxa yezizathu ezifanelekileyo.

Ndingayinyusa njani i-NAD yam + ngokwendalo?

Ukunyusa ngokwendalo amaNqanaba eNAD

  • Ukuzila
  • Izongezo zeNicotinamide Riboside
  • Lolonga
  • Ukukhanya kwelanga okuninzi kunokuba kungalungi!
  • Ukutya okuphucula amanqanaba e-NAD

Kufuneka ndize nantoni ne-NMN?

Ukuphucula amanqanaba akho e-NAD, ungathatha iipilisi zeNMN zokulibaziseka ngeSirtuin Activator enje ngeResveratrol eneyogathi egcwele amanqatha enceda ukubakho kweResveratrol.

Ngaba kufuneka ndithathe i-TMG nge-NMN?

Ukuba ngoku uthatha i-NMN okanye ucinga ngokuqala, cinga ngokudibanisa ne-TMG njengenkxaso eyongeziweyo ye-methylation. Abanye abanikeli be-methyl abanokuba luncedo kubandakanya i-methylated B6, B12, kunye ne-folate.

Uyintoni umahluko phakathi kwenicotinamide kunye nenicotinamide riboside? (3)

I-Niacin luhlobo lwe-nicotine oluguqulweyo olunokuthi umzimba uguqulwe ube yi-NAD. INicotinamide yi-amide ye-niacin efana kakhulu ne-NAD kwaye ineziphumo ebezingalindelekanga ezimbalwa. I-Nicotinamide riboside yindlela yokwenziwa kwe-nicotinamide eneempawu ezahlukeneyo.

Ngaba i-Nmn yi-niacin?

Njenge-nicotinamide riboside, i-NMN sisiphumo se-niacin, kwaye abantu banee-enzymes ezinokusebenzisa i-NMN ukuvelisa i-nicotinamide adenine dinucleotide (NADH). Kwiimpuku, i-NMN ingena kwiiseli ngamathumbu amancinci ngaphakathi kwemizuzu eli-10 iguqula i-NAD + ngeSlc12a8 NMN yokuhambisa.

Ngaba i-nicotinamide riboside isezantsi i-BP?

I-Nicotinamide riboside yinto eyenzeka ngokwendalo ye-nicotinamide adenine dinucleotide (NAD +), umlamli obaluleke kakhulu kwiziphumo zothintelo lwekhalori, ngenxa yoko inoveli yekhalori yokuthintela imimetic compound. Kutshanje sigqibe isifundo sokuqala somlinganiso we-nicotinamide riboside supplementation kubantu abadala abasempilweni nabadala kwaye sabonisa ukuba iiveki ezi-6 zokuncedisa zinciphise uxinzelelo lwegazi (SBP) nge-8 mmHg kubantu abane-SBP esisiseko ye-120-139 mmHg (iphakanyisiwe i-SBP / Isigaba 1 soxinzelelo lwegazi) xa kuthelekiswa ne-placebo, kunye nokuthomalalisa ukuqina komzimba, isimilo esomeleleyo esizimeleyo se-CVD kunye nokugula okukhoyo kunye nokufa.

Ifumaneka phi i-betaine?

I-Betaine ifumaneka kwi-microorganisms, kwizityalo nakwizilwanyana kwaye yinto ebalulekileyo kukutya okuninzi, kubandakanya ingqolowa, iqokobhe, isipinatshi kunye neeswekile. I-Betaine sisixhobo se-zwitterionic quaternary ammonium esikwabizwa ngokuba yi-trimethylglycine, glycine betaine, lycine, kunye ne-oxyneurine.

Kukuphi ukutya okumisa imibimbi?

Nazi izinto ezilishumi zokutya ezichasene nokwaluphala ukuze wondle umzimba wakho ngokukhanya okuvela ngaphakathi.

  • Watercress
  • Ipelepele ebomvu yentsimbi
  • Ipapaya
  • aluhlaza
  • Ibrokholi
  • Ispinatshi
  • ngomane
  •  
  • Iitapile ezimnandi
  • Imbewu yePomegranate

Ndingajongeka njani ndimncinci ngeminyaka eli-10?

  • Sebenzisa iMask yokuHamba.
  • Khetha iSiseko seLuminous
  • Khanyisa iinwele zakho kancinci
  • Nxiba iPonytail
  • Ukukhupha kwakhona (kodwa ungadluli)
  • Mhlophe uManzi wakho
  • Gqibezela ukuKhangela ngeNgcaciso yeMaminerali

Ndingabumisa njani ubuso bam ekwaluphaleni?

  • Khusela ulusu lwakho elangeni yonke imihla
  • Faka isicelo sokuzicoca ngokwakho kunokuba ufumane itan
  • Ukuba uyatshaya, yeka
  • Kulumkele ukuphindaphinda imbonakalo yobuso
  • Yitya ukutya okusempilweni, okunesondlo
  • Sela utywala obuncinci
  • Zilolonge iintsuku ezininzi zeveki
  • Coca ulusu lwakho ngobunono

Kukuphi ukutya okukwenza ukhawuleze ukhawuleze?

  1. Iitapile zamazambane aswiti eefrench
  2. Isonka esihluthiweyo sesonka esimhlophe
  3. Ubusi okanye iziqhamo zeswekile emhlophe
  4. Ioyile yomnquma okanye iiavokhado zemargarine
  5. Namathela kwiinkukhu zenyama ehleliweyo
  6. Yiva ubisi
  7. Cinga kabini ngesoda kunye nekofu
  8. Sela utywala ngobungcathu
  9. Gwema ukupheka ngokushisa okukhulu
  10. Cima iikeyiki zerayisi
  11. I-Counteract fructose ene-lipoic acid

Yeyiphi ivithamini elungileyo kwimibimbi yobuso?

I-Vitamin C inokukunceda ukukhusela iimpawu zokwaluphala ngenxa yendima yayo ebalulekileyo kulwakhiwo lomzimba lwe-collagen. Kuyanceda ukuphilisa ulusu olonakeleyo kwaye, kwezinye iimeko, kunciphisa ukubonakala kwemibimbi. Ukutya ngokwaneleyo i-vitamin C kunokunceda ekulungiseni nasekuthinteleni ulusu olomileyo.

Kutheni sifuna iNicotinamide Mononucleotide (NMN)?

Ukuguga kunxulumene nexesha kunye nokuncedwa kwexesha lokuphinda kubuyiswe kwimisebenzi yomzimba womntu. Nangona ukuguga kungenakuphepheka kwaye kungenakuthintelwa, izazinzulu zinikele iminyaka ekuqondeni ukuba le nkqubo ingalibaziseka kwaye ilawulwe njani. Olu phando luqhubekileyo lukhokelele ekufumanekeni kwezinto ezininzi kunye nezinto ezinento yokwenza nokuguga ezinokuguqulwa zibe zizongezo ezichasene nokwaluphala. Enye yezi zinto zinento ebalulekileyo yokulwa ukwaluphala eneenzululwazi eziziva zinomdla yiNMN okanye iNicotinamide Mononucleotide. Kule nqaku, sixoxa ngayo yonke into ekufuneka siyazi malunga ne-NMN kunye nesona saphulelo sokuguga se-nicotinamide mononucleotide ngo-2021.

Ukusetyenziswa kweNicotinamide Mononucleotide (NMN)

Kude kube yiminyaka embalwa edlulileyo, zonke izifundo ezinxulumene nokusetyenziswa kwe-NMN bezisenziwa kwizilwanyana kwaye ngelixa ezi zifundo zibonisa iziphumo ezithembisayo, ezi ziphumo bezingonelanga ukuseka izibonelelo zokusetyenziswa kwe-NMN ebantwini. Ngo-2016, kwaqhutywa isifundo ukuhlalutya ukhuseleko lokusetyenziswa kwe-NMN kunye nexesha layo kwigazi lomntu. Isifundo sihambise iziphumo ezithembisayo. Thumela ukuba, olunye uphando luqhutywe ngo-2016 ukufundisisa umphumo wokusetyenziswa kwe-NMN kwabasetyhini abadala abangama-50 abane-BMI ephezulu, i-glucose yegazi kunye ne-triglycerides yegazi. Isifundo siphumelele. Nangona kunjalo, kuba umhlaba wokufunda wawunqunyelwe kuphela kwabasetyhini abakwiminyaka ethile, izazinzulu zazikholelwa ekubeni ubungqina obungakumbi bufuneka ukufumanisa ukuba ukusetyenziswa kweNMN kukhuselekile ebantwini.

Ke ngoko, kutsha nje, kwi-2019, isifundo senziwe kwiCandelo loLingo lweKlinikhi leKeio University School of Medicine. Umxholo wophando yayingamadoda ali-10 aneminyaka ephakathi kwama-40 nama-60. La madoda afakwa iidosi ukusuka kwi-100 mg ukuya kwi-500 mg. Isifundo sigqibe kwelokuba i-NMN inyamezeleke kakuhle ngabantu kwaye ikhuselekile ukuba ingasetyenziswa ukuba nje ukusetyenziswa kwayo kulawulwa kakuhle. Olu phononongo lwalubalulekile njengoko yayiluvavanyo lokuqala lwe-NMN olwenziwe ebantwini lokufunda isiphumo se-NMN kwimpilo yoluntu ngokubanzi. Kwakamsinya nje ukuba kusekwe ukuba ukusetyenziswa kwe-NMN kukhuselekile, abavelisi baqala ukuqhushumbisa imarike ngezongezo zeNMN, eziqheleke kakhulu kwezi ntsuku. (2) Yoshino, J., et al. (2011)….

benefits

Kweli candelo, sixoxa ngezibonelelo ezinokubakho ezinxulunyaniswa neNicotinamide Mononucleotide okanye izibonelelo zeNMN.

I-NMN inciphisa ukuguga

Enye yezona nzuzo zibalaseleyo ze-NMN kukuba kunciphisa inkqubo yokuguga. Kwiminyaka embalwa edlulileyo, uDavid Sinclair, ugqirha webhayoloji odumileyo wase-Australia kunye noprofesa weGenetics, wanikela ubungqina bokuba i-NAD + iyacothisa ukuguga kunye nokuqala kwezifo ezinxulumene nobudala ebantwini. Nangona kunjalo, ukuveliswa kweNAD + kunciphisa ngobudala. Ke, njengoko abantu bekhula, isidingo sangaphambi kwe-NAD + siyanda ngaphakathi kwemizimba yabo. Kulapho i-NMN iqala khona ukudlala: I-NMN ingena kwiiseli kwaye iguqulwe ngemichiza emininzi ngaphambi kokuba iguqukele kwi-NAD + kwaye inciphise iinkqubo zokuphelisa ubudala.

② Abantu abaPhethwe sisifo seSwekile banokuxhamla ekusebenziseni kwaso

Kwaqhutywa isifundo sokufunda indlela isongezelelo somlomo se-NMN esinceda ngayo ekutyeni nakwisifo seswekile esimalunga nobudala kwiimouse. Uphononongo luveze ukuba iimpuku ezinikezwe ngomlomo ze-NMN ziyabonakalisa ukonyuka kweemvakalelo nge-insulin kunye nokukhuseleka kwayo okuthe kratya. Olu pho nonongo lubonelele ukuba iNicotinamide Mononucleotide okanye i-NMN isongezelelo ngomlomo sinokunceda abantu abanesifo seswekile.

Cons Ukusetyenziswa kweNMN kukwaNxulunyaniswa neMpilo yeNtliziyo ephuculweyo

Olunye uphononongo lwenzelwa ukufunda ngendlela i-NMN supplementation eyichaphazela ngayo impilo yeentliziyo kwiimpuku Uhlolisiso luveze ukuba i-NMN ayibuyisi kuphela umchiza wegazi onxulumene nobudala kunye nomonakalo we-capillary kwiimpuku kodwa wakhokelela nasekuphuculeni ukuhamba kwegazi. Eyona nto yandothusa kakhulu yinto yokuba kwiigundane ezinikwe i-NMN isongezelelo ngomlomo, ukuqhuma kwemithambo yegazi emitsha kwaqatshelwa. Kutshanje, kuye kwenziwa olunye uphando ukuze kufunyanwe iimpembelelo ze-NMN kwimpilo yeendlebe kwaye olu phando luveze iziphumo ezifanayo. Ezi zifundo zinikeze ubungqina obaneleyo kubaphandi ukuba bakholelwe ukuba ukusetyenziswa kwe-NMN kukhuthaza impilo yentliziyo ebantwini.

INicotinamide Mononucleotide (NMN)

④ Abantu abaneAlzheimer's banokuzuza kuNcedo lweNMN

Kubantu abaphethwe sisifo i-Alzheimer, amanqanaba e-NAD ayehla kakhulu. Ke, xa abantu abanesifo se-Alzheimer besebenzisa i-NMN, umzimba uphendula ngokwandisa inani le-NAD +, ethi yona ikhokelele ekwandeni kolawulo lweemoto, inyuse i-SIRT3 yemfuza, inkumbulo ephuculweyo kunye nokunciphisa i-neuroinfigueation. Ke, abantu abane-Alzheimer's banokuxhamla ngokutya I-NMN.

I-NMN ikwaphucula ukusebenza kweZintso

Isongezelelo somlomo se-NMN sidityaniswa nomsebenzi ophuculweyo wezintso. Kungenxa yokuba i-NMN yonyusa imveliso ye-NAD + kunye ne-SIRT1, yomibini edityaniswa nomsebenzi owandisiweyo wezintso.

Ungayithenga phi iNicotinamide Mononucleotide (NMN) Powder ngobuninzi?

Ukuba ujonge ukuthenga iNicotinamide Mononucleotide (NMN) powder ngobuninzi, eyona ndawo ifanelekileyo yokuthenga i-NMN powder yile cofttek.com. I-Cofttek lishishini lobuchwephesha obuphezulu elinika imveliso kunye nomgangatho ophezulu ukusukela ngo-2008. Inkampani iyaqhayisa ngeqela le-R & D elinomtsalane elinabantu abanamava abazinikele kuphuhliso lweemveliso ezikhuphisanayo. Cofttek inamaqabane kwaye inikezela ngeemveliso zayo kwiinkampani ezixuba amayeza e China, Europe, India nase North America. I-Nic-Nicotinamide Mononucleotide ekhutshwa yiCofttek ikumgangatho ophezulu kakhulu kwaye ikhuseleke ngokupheleleyo ukuba isetyenziswe ngabantu. Okubaluleke ngakumbi, inkampani ibonelela ngalo mgubo ngobuninzi, okt kwiiyunithi ezingama-25kgs. Ke, ukuba ujonge thenga le powder ngobuninzi, I-Cofttek yinkampani ekufuneka unxibelelane nayo-zezona zinto zibonelela nge-Nicotinamide Mononucleotide (NMN) yomthengisi we powder kwimarike.

INicotinamide Mononucleotide (NMN) infogram
INicotinamide Mononucleotide (NMN) infogram
INicotinamide Mononucleotide (NMN) infogram
Isiqendu ngo:

UGqirha Zeng

Umququzeleli, ubunkokheli bobunkokheli kwinkampani; I-PhD ifunyenwe kwiYunivesithi yaseFudan kwi-organic chemistry. Ngaphezulu kweminyaka esithoba yamava kwi-organic chemistry kunye noyilo lweziyobisi synthesis; phantse i-10 lamaphepha ophando apapashwe kwiijenali ezigunyazisiweyo, nangaphezulu kweepatent ezintlanu zase China

Ucaphulo

(1). Yao, Z., et al. (2017). INicotinamide Mononucleotide inhibisha ukwenziwa kweJNK ukubuyisa isifo seAlzheimer.

(2). UYoshino, uJ., Et al. (2011). INicotinamide Mononucleotide, i-NAD ephambili (+) ePhakathi, inyanga iPathophysiology yokutya kunye nesifo seswekile esidala kwiigundane. Iseli yeMetabolism.

(3). Yamamoto, T., okqhubekayo. (2014). I-Nicotinamide Mononucleotide, ephakathi kwe-NAD + Synthesis, Ikhusela Intliziyo kwi-Ischemia kunye neReffusion.

(4). UWang, Y., et al. (2018). Ukongezwa kwe-NAD + kulungelelanisa iiMpawu zeAlzheimer eziphambili kunye neempendulo zomonakalo weDNA kwiModeli eNtsha yeMouse ye-AD kunye neNzelelo yokuLungiswa kweDNA.

(5). UKeisuke, O., et al. (2019). Iziphumo zokutshintsha kweMetabolism ye-NAD kwiNgxaki yeMetabolic. Ijenali yeeNzululwazi zeBiomedical.

(6). Uhambo lokujonga umz.

(7). I-Oleoylethanolamide (oea) -i-wand yemilingo yobomi bakho.

(8). I-Anandamide vs cbd: yeyiphi engcono kwimpilo yakho? Yonke into ekufuneka uyazi ngabo!

(9). Yonke into ofuna ukuyifumana malunga ne-nicotinamide riboside chloride.

(10). Izongezo zeMagnesium l-threonate: izibonelelo, idosi, kunye neziphumo ebezingalindelekanga.

(11). Palmitoylethanolamide (ertyisi): izibonelelo, idosi, ukusetyenziswa, isongezelelo.

(12). Izibonelelo zezempilo ezi-6 eziphezulu ze-resveratrol supplements.

(13). Izibonelelo ezi-5 eziphezulu zokuthatha i-phosphatidylserine (ps).

(14). Izibonelelo ezi-5 eziphezulu zokuthatha i-pyrroloquinoline quinone (pqq).

(15). Olona hlobo longezelelekileyo lwe-alpha gpc.