Umvelisi weOleoylethanolamide (OEA) (111-58-0) -uCofttek

I-Oleoylethanolamide (i-OEA) (111-58-0)

Aprili 7, 2020

I-Oleoylethanolamine (OEA) yindalo eyenzeka ngokwemvelo i-ethanolamide lipid kunye ne-receptor peroxisome proliferator-activated receptor-α (PPAR-α) agonist. Kuveliswa amathumbu amancinci kwaye kuthintele ukungena ngaphakathi ku-PPAR-α.

 


Isimo: KwiMveliso yoLuntu
Iyunithi: 1kg / ingxowa, 25kg / Igubu

I-Oleoylethanolamide (OEA) (111-58-0) ividiyo

 

I-Oleoylethanolamide (OEA) Suqobo

igama: I-Oleoylethanolamide (OEA)
CAS: 111-58-0
Ukungcola 98%
Ifomula yeMolekyuli: C20H39NO2
Ubunzima Ezinto: 325.53 g / mol
Melt Point: 59-60 ° C
Igama leKhemikhali: U-N-Oleoylethanolamide
Iintetho: N-Oleoylethanolamine, N- (Hydroxyethyl) oleamide, N- (cis-9-Octadecenoyl) ethanolamine, OEA
InChI Key: I-SUHOQUVVLLYYQR-MRVPVSSYSA-N
Ubomi obulicla: N / A
Umzimba: I-soluble kwi-DMSO, Methanol, Amanzi
Umbandela woGcino: 0 - 4 C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20 C ixesha elide (iinyanga)
isicelo: I-Oleoylethanolamide (OEA) yi-metabolite yendalo eyenziwe ngamanani amancinci kwisisu sakho esincinci. I-OEA inceda ukulawula ukulamba, ubunzima, amanqatha omzimba kunye ne-cholesterol ngokubopha kwi-receptor eyaziwa ngokuba yi-PPAR-Alpha (Peroxisome proliferator-activated receptor alpha).
Kubonakala: Powder

 

Yintoni iOleoylethanolamide (OEA) CAS 111-58-0?

I-Oleoylethanolamine (OEA) yindalo eyenzeka ngokwemvelo i-ethanolamide lipid kunye ne-receptor peroxisome proliferator-activated receptor-α (PPAR-α) agonist. Kuveliswa amathumbu amancinci kwaye kuthintele ukungena ngaphakathi ku-PPAR-α. I-OEA iphinda isebenze i-GPR119, i-lipid esebenzayo ye-bioactive ene-hypophagic kunye ne-anti-obeship effect.

 

Oleoylethanolamide (OEA) CAS 111-58-0 izibonelelo

I-Oleoylethanolamide (OEA) yi-metabolite yendalo eyenziwe ngamanani amancinci kwisisu sakho esincinci. I-OEA inceda ukulawula ukulamba, ubunzima, amanqatha omzimba kunye ne-cholesterol ngokubopha kwi-receptor eyaziwa ngokuba yi-PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). Eyona nto ibalulekileyo, i-OEA inyusa imetabolism yamafutha omzimba kwaye ixelele ubuchopho bakho ukuba ugcwele kwaye lixesha lokuba uyeke ukutya. I-OEA yaziwa ngokuba yandisa inkcitho yeekhalori ezingasebenziyo.

 

I-Oleoylethanolamide (OEA) CAS 111-58-0 Indlela yokusebenza?

I-Oleoylethanolamide (i-OEA) idityanisiwe yadityaniswa kwisisu esincinci esincinci esivela kukutya okufumaneka kwi-oleic acid, enje ngeoyile yomnquma. Ukutya okunamafutha aphezulu kunokuthintela ukuveliswa kwe-OEA emathunjini. I-OEA inciphisa ukutyiwa kokutya ngokwenza ukuba i-homeostatic oxytocin kunye ne-histamine brain circry kunye ne-hedonic dopamine pathways. Kukho ubungqina bokuba i-OEA inokunciphisa i-hedonic cannabinoid receptor 1 (CB1R) ukusayina, ukwenziwa kwayo okunxulunyaniswa nokwanda kokutya. I-OEA inciphisa ukuthuthwa kwe-lipid kwii-adipocyte ukunciphisa ubunzima bamafutha. Ukucaciswa ngakumbi kweziphumo ze-OEA kukutya kunye ne-lipid metabolism kuya kunceda ekumiseleni iindlela zomzimba ezinokuthi zijolise ekuphuhliseni unyango olusebenzayo.

I-Oleoylethanolamide (i-OEA) yi-agonist ye-peroxisome proliferator-activated receptor-α (PPAR- α). I-N- Oleoylethanolamide ivelisa uphawu lwamathumbu oluvuselela umsebenzi ophakathi we-dopamine ukuseka ikhonkco phakathi kwe-caloric- homeostatic kunye ne-hedonic- homeostatic controllers. I-Oleoylethanolamide inyanzelisiwe njengesixhobo seemolekyuli ezinxulumene nempumelelo yokudlula kwesisu. N- Oleoylethanolamide yi-GPR55 agonist ekhethiweyo.

 

I-Oleoylethanolamide (OEA) CAS 111-58-0 isicelo

I-Oleoylethanolamide (i-OEA) isebenza ukwenza into ebizwa ngokuba yi-PPAR kwaye kwangaxeshanye inyusa ukutshiswa kwamafutha kunye nokunciphisa ukugcinwa kwamafutha. Xa usitya, amanqanaba e-OEA anda kunye nomnqweno wakho wokutya uyancipha xa imithambo-luvo yeemvakalelo enxibelelana nengqondo yakho isixelela ukuba ugcwele. I-PPAR-α liqela le-ligand-activated nuclear receptor ebandakanyeka ekubonakalisweni kohlobo lwe-lipid metabolism kunye ne-energyhomeostasis pathways.

 

I-Oleoylethanolamide (OEA) powder kwintengiso(Apho uthenge khona iOleoylethanolamide (OEA) umgubo ngobuninzi)

Inkampani yethu iyonwabela ubudlelwane bexesha elide kunye nabaxumi bethu kuba sigxile kwinkonzo yabathengi kunye nokubonelela ngeemveliso ezintle. Ukuba unomdla kwimveliso yethu, siyaguquguquka ngendlela eqhelekileyo yokwenza ii-odolo ukuze zilungele iimfuno zakho ezithile kunye nexesha lethu elikhawulezayo lokufumana iiodolo uqinisekisa ukuba uyayiva imveliso yethu kwangexesha. Sijolise kwakhona kwiinkonzo ezongezwe ngexabiso. Sifumaneka kwimibuzo yenkonzo kunye nolwazi lokuxhasa ishishini lakho.

Singumthengisi weOleoylethanolamide (OEA) ongumthengisi we powder iminyaka eliqela, sinikezela ngeemveliso ngexabiso elikhuphisanayo, kwaye imveliso yethu ikumgangatho ophezulu kwaye iyavavanywa ngokungqongqo, nokuzimela ukuqinisekisa ukuba kukhuselekile ukusetyenziswa kwihlabathi liphela.

 

Ucaphulo

  1. UGaetani S, Oveisi F, uPiomelli D (2003). "Ukumodareyitha kwipateni yokutya kumgangatho yi-anorexic lipid mediator oleoylethanolamine". Neuropsychopharmacology. 28 (7): 1311-6. ikhonkco: 10.1038 / sj.npp.1300166. IINKCUKACHA:
  2. ULo Verme J, uGaetani S, uFu J, u-Oveisi F, uBurton K, uPiomelli D (2005). "Ummiselo wokutya ngokutya yi-oleoylethanolamine". Iseli. Umlomo. Inzululwazi yoBomi. 62 (6): 708-16. ikhonkco: 10.1007 / s00018-004-4494-0. IINKCUKACHA:
  3. UGaetani S, Kaye WH, uCuomo V, uPiomelli D (Septemba 2008). "Indima ye-endocannabinoids kunye ne-analogs yabo ekutyebeni kakhulu kunye nokuphazamiseka kwindlela yokutya". Yitya ukungahambi kakuhle. 13 (3): e42-8. IINKCUKACHA: