IColuracetam (135463-81-9)

Ngamana 8, 2021

ICofttek yeyona mveliso ilungileyo yeColuracetam yomgubo eTshayina. Umzi-mveliso wethu unenkqubo epheleleyo yolawulo lwemveliso (ISO9001 & ISO14001), kunye nemveliso yenyanga eyi-160kg.

 


Isimo: KwiMveliso yoLuntu
Iyunithi: 1kg / ingxowa, 25kg / Igubu

IColuracetam (135463-81-9) Suqobo

igama: IColuracetam
CAS: 135463-81-9
Ukungcola 98%
Ifomula yeMolekyuli: C19H23N3O3
Ubunzima Ezinto: I-341.411 g / imoll
Melt Point: N / A
Igama leKhemikhali: N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

I-MKC-231

Iby-540

Iintetho: I-Coluracetam; I-BCI-540; I-MKC-231; I-BCI 540; I-MKC 231; BCI540; MKC231.
InChI Key: PSPGQHXMUKWNDI-UHFFFAOYSA-N
Ubomi obulicla: N / A
Umzimba: Isisombululo kwiDMSO
Umbandela woGcino: Okomileyo, omnyama kunye no-0 ukuya ku-4 C okwexesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka)
isicelo: I-Raw Coluracetam powder (i-MKC-231) isichengechunge se-racetam esicelwa ukuba sibe yi-nootropic compound.
Kubonakala: powstalline powder

 

IColuracetam (135463-81-9) I-Spectrum yeNMR

IColuracetam (135463-81-9) I-Spectrum yeNMR

Ukuba ufuna i-COA, i-MSDS, i-HNMR kwibhetshi nganye yemveliso kunye nolunye ulwazi, nceda unxibelelane nathi umalwuli wezentengiso.

 

Yintoni i IColuracetam (135463-81-9)?

I-Raw Coluracetam powder (i-MKC-231) isichengechunge se-racetam esicelwa ukuba sibe yi-nootropic compound. Ingenawo ubungqina obuninzi bokuphanda, kodwa iindlela zokusebenza (kunye nesakhiwo) zibonakala zihluke kakhulu kwezinye i-racetam ezinjengePiracetam okanye i-Aniracetam.

I-Raw Coluracetam powder ibonakala idibanisa nenkqubo eyaziwa ngokuba yintsebenziswano ephezulu ye-choline (i-HACU efutshane), eyona nqanaba lokunciphisa izinga lokudweba i-neuron ukuze ihlanganiswe kwi-neurotransmitter acetylcholine. Ukwandisa izinga le-HACU kubonakala kunyuse umsebenzi we-nelinon cholinergic, ngoko kukujoliswe ekujoliseni ukuphuculwa kwengqondo.

 

IColuracetam (135463-81-9) iinzuzo

  • Ukuphucula inkumbulo kunye nokufunda
  • Phucula ukuqondwa kokufunda kunye nokukhumbula okuSimahla
  • Ukuphuculwa kokuqonda ixesha elide
  • Ukunciphisa Unyango-Lwaxinezeleko Uxinzelelo
  • Inkuthazo enokubakho yeNeurogeneis
  • Inokuphucula ukukhubazeka kwengqondo
  • Kwanga kungaphuculwa umbono
  • Ukuphuculwa kweempawu zeBrael Syndrome
  • Ukusetyenziswa kokuzonwabisa kweColuracetam

 

IColuracetam (135463-81-9) setyenziso

IColuracetam (INN) (igama lekhowudi i-BCI-540; eyayisakuba yi-MKC-231) umgubo yiarhente ye-nootropic yosapho lwe-racetam. Yaqala yaphuhliswa kwaye yavavanywa yiMitsubishi Tanabe Pharma Corporation yesifo se-Alzheimer's. Emva kokuba iyeza lingaphumelelanga ukufikelela kwiziphelo kwizilingo zeklinikhi yayinikwe ilayisensi yiBrainCells Inc yophando kwisifo esikhulu sokudakumba (MDD), esasandulelwa ngokunikezelwa kwe "Grantifying Therapy Discovery Programme Grant" ngurhulumente waseCalifornia.

 

IColuracetam (135463-81-9) Isistim

Ininzi yophando kwi-coluracetam yenziwe kwizilwanyana kunabantu, ngoko akukho zikhokelo zokufumana iifom. Uluhlu lwamathamo osebenzayo luchazwe ngokubanzi njenge-5-20 mg. Abasebenzisi be-coluracetam baye baxela uluhlu olubanzi lwee-doses ezilawulwa ngokusemthethweni nangokwezantsi.

Ingxelo yomsebenzisi ikwakhankanye ukuba ukunyamezelana ne-coluracetam powder kunokukhula ngokukhawuleza. Njengawo onke amayeza, ngakumbi ii-nootropics, kungcono ukuqala kwiidosi ezincinci kunye nokunyusa idosi ngokuthe ngcembe njengoko umzimba wakho usabela kwaye uguqula amayeza. IColuracetam ayiyityhefu kwaye ithathwa njengeyonyamezeleke kwaye ikhuselekile.

 

I-coluracetam powder kwintengiso(Kuphi ukuthenga i-Coluracetam powder ngobuninzi)

Inkampani yethu iyonwabela ubudlelwane bexesha elide kunye nabaxumi bethu kuba sigxile kwinkonzo yabathengi kunye nokubonelela ngeemveliso ezintle. Ukuba unomdla kwimveliso yethu, siyaguquguquka ngendlela eqhelekileyo yokwenza ii-odolo ukuze zilungele iimfuno zakho ezithile kunye nexesha lethu elikhawulezayo lokufumana iiodolo uqinisekisa ukuba uyayiva imveliso yethu kwangexesha. Sijolise kwakhona kwiinkonzo ezongezwe ngexabiso. Sifumaneka kwimibuzo yenkonzo kunye nolwazi lokuxhasa ishishini lakho.

Singumthengisi weColuracetam ongumgubo iminyaka eliqela, sinikezela ngexabiso elinokhuphiswano, kwaye imveliso yethu ikumgangatho ophezulu kwaye iyavavanywa ngokungqongqo, nokuzimela ukuqinisekisa ukuba kukhuselekile ukusetyenziswa kwihlabathi liphela.

 

Ucaphulo

[1] UAkaike A, et al. (1998). Iziphumo ezikhuselayo zeMKC-231, inoveli ephezulu yokuqina kwe-choline yokunyusa, kwi-glutamate cytotoxicity kwii-cortical neurons. IJpn J Pharmacol.

[2] UBessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., kunye noSaito, K. (1996). Iziphumo zenoveli yokuhlangana okuphezulu kwe-choline yokunyusa ukuphucula 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) i-acetoamide kusilelo lokufunda kwamanzi kwiigundane. IArzneimittel-Forschung, 46 (4), 369-373.

[3] UMurai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., kunye no-Itoh, T. (1994). I-MKC-231, i-choline yokuthabatha isithuthukisi, yonyusa ukusilela kwememori yokusebenza kunye nokunciphisa i-hippocampal acetylcholine ebangelwa yi-ethylcholine aziridinium ion kwiimpuku. Ijenali yokuhanjiswa kweNeural, 98 (1), 1-13 / bf10.1007 / bf01277590 (PubMed) (Umnqamlezo)

[4] UTakashina K, uBessho T, uMori R, uEguchi J, uSaito K. MKC-231, isiphuculo sokuvuselelwa kwe-choline: (2) Iziphumo kwifomathi kunye nokukhutshwa kwe-acetylcholine kwiigundane eziphathwe yi-AF64A. J Neural Transm (Vienna). Ngo-2008 uJul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. I-PubMed PMID: 18446264.

[5] I-Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Ukuchazwa okulandelayo kwesithintelo se-choline ekuphuculeni isimilo se-MKC-231 kuchasene ne-phencyclidine-in indosicocents yokuziphatha yokuziphatha kunye nokunciphisa i-septal cholinergic neurons in rats. I-Euro Neuropsychopharmacol. Ngo-2007 Sep; 17 (9): 616-26. I-PubMed PMID: 17467960.