Ukubonisa 1-12 kweziphumo 37

CAS NO. IGAMA LEMVELISO AMAGQABANTSHINTSHI
    552325-73-2 A-674563 (552325-73-2)

    I-674563 inamandla, i-akt1 inhibitor ngomlomo enexabiso le-IC50 ye-11nM. Ubonisa kwakhona umsebenzi olwa nePKA kunye neCDK2 ngexabiso le-IC50 ...

    1047634-63-8 Afuresertib (GSK2110183) (1047634-63-8)

    I-GSK2110183 ngumlomo ongenakufumaneka, okhethiweyo, okhuphiswano lwe-ATP kunye ne-pan-Aktinhibitor ene-IC50 ye-0.08 / 2 / 2.6 nM ye-Akt1 / Akt2 / Akt3 ...

    487021-52-3 AR-A014418 (487021-52-3)

    I-AR-A014418 yi-ATP-ukhuphiswano, kunye ne-GSK3β inhibitor ene-IC50 kunye ne-Ki ye-104 nM kunye ne-38 nM, ngaphandle kokuvimbela okukhulu kwi-26 ...

    1056901-62-2 I-AT13148 (1056901-62-2)

    I-AT13148 iyinveli, inomlomo emininzi ye-AGC i-inhibitor ene-pharmacodynamic kunye ne-antitumor; AKT, p70S6K, PKA, ROCK, kunye neSGK inhib ...

    857531-00-1 I-AT7867 (857531-00-1)

    I-AT7867 yi-inhibitor enamandla ye-ATP-Akt1 / 2 / 3 kunye ne-P70S6K / PKA kunye ne-IC50 ye-32 nM / 17 nM / 47 nM kunye ne-85 nM / 20 nM, ngokulandelanayo; ncinane ...

    612487-72-6 I-AZD1080 (612487-72-6)

    I-AZD1080 yindlela ekhethiweyo, ngomlomo, esebenzayo, engqondweni ye-GSK3 inhibitor, inhibits i-GSK3A yabantu kunye ne-GSK3β kunye ne-Ki ye-6.9 nM kunye ne-31 nM, elandelayo ...

    486424-20-8 I-AZD2858 (486424-20-8)

    I-AZD2858 inamandla kunye ne-GSK-3 inhibitor ene-IC50 ye-68 nM. I-AZD-2858 inqanda i-tau phosphorylation kwisiza se-S396, kwaye yenza i-Wnt s ...

    1143532-39-1 I-AZD5636 (1143532-39-1)

    I-AZD5363, eyaziwa nangokuthi yiCapivasertib, i-inhibitor yomlomo nge-serine / threonine protein kinase i-AKT (iprotheni kinase B) enepote ...

    188011-69-0 I-Bikinin (188011-69-0)

    I-Bikinin (i-Abrasin) inhibitor enamandla yesityalo GSK-3 / Shaggy-like kinase; yenza i-BR ibonakalise ngaphantsi kwe-BR receptor.

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    1007207-67-1 CH5132799 (1007207-67-1)

    I-CH5132799 inqanda iklasi I-PI3Ks, ngokukodwa i-PI3Kα ne-IC50 ye-14 nM; ngaphantsi kwePI3Kβδγ, ngelixa uvalelekile kwi-PIK3CA utshintsho lweself ...

    252935-94-7 I-CHIR-98014 (252935-94-7)

    I-CHIR-98014 yi-GSK3 inhibitor ekhethiweyo ye-IC50 ye-0.65 nM kunye ne-0.58 nM ye-GSK-3A ne-GSK-3β; i-insulin isebenze ukusebenza kwe-glucose tr ...

    915019-65-7 Dactolisib (BEZ235) (915019-65-7)

    I-BEZ235 (i-NVP-BEZ235) i-PPNNXX kunye ne-TT inhibitor ye-ATP ye-P3 /// kunye ne-MTOR (p110S70K) kunye ne-IC6 ye-50 nM / 4 nM / 5 nM / 7 nM / 75 nM, i-...