Ebonisa zonke iziphumo 11

CAS NO. IGAMA LEMVELISO AMAGQABANTSHINTSHI
    1668553-26-1 A-1210477 (1668553-26-1)

    I-1210477 iyinamandla kwaye ikhetha i-MCL-1 inhibitor ne-Ki kunye ne-IC50 ye-0.454 nM kunye ne-26.2 nM, ngokulandelanayo,> Ukukhethwa kwe-100 ngokukhethiweyo ngaphezulu ...

    1426138-42-2 FX1 (1426138-42-2)

    I-FX1 inamandla kwaye ikhethekileyo ye-BCL6 inhibitor, kunye ne-IC50 ye-35 μM.FX1 inhibitor ye-B cell lymphoma 6 (BCL6). ....

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    803647-40-7 NSC59984 (803647-40-7)

    I-NSC59984 yenza inkunkuma ye-p53 iguqulwe nge-MDM2 kunye ne-ubiquitin-proteasome pathway. I-EC50 ye-NSC59984 kuninzi iiseli zomhlaza ...

    1313363-54-0 I-NVP-CGM097 (1313363-54-0)

    I-NVP-CGM097 (i-CGM-097) iyona nto inamandla kwaye ikhetha i-MDM2 inhibitor; umququzeleli womlomo we-HDM2 ngomlomo onomsebenzi onokuthi u-antineoplastic & #

    803712-79-0 I-Obatoclax Mesylate (GX15-070) (803712-79-0)

    I-Obatoclax Mesylate (i-GX15-070) ngumchasi weBcl-2 kunye ne-Ki ye-0.22 μM kwisilingo esingenalutho, unokuncedisa ekunqobeni i-MCL-1 umlamli odibeneyo ...

    939981-39-2 RG7112 (939981-39-2)

    I-RG7112 yinkqubo yokuqala ye-kliniki encinci i-MDM2 inhibitor eyenzelwe ukuhlala ipokotho ye-p53-binding ye-MDM2 ....

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    1229705-06-9 RG7388 (1229705-06-9)

    I-RG7388 ngumlomo, okhethiweyo, omncinci we-molecular MDM2 ovimbela ukubopha kwe-MDM2 kwi-p53. Idasanutlin, eyaziwa ngokuba yi-RG7388 ne-RO55 ...

    1309684-94-3 RO8994 (1309684-94-3)

    I-RO8994 yinkqutyana enamandla kwaye ikhethiweyo ye-spiroindolinone encinci-molecule i-MDM2 inhibitor, kunye ne-IC50 ye-5 nM (i-HTRF yokulinganisa iilingo) kunye ...

    1262888-28-7 I-Spautin-1 (1262888-28-7)

    I-Spautin-1 yi-inhibitor ye-autophagy inoveli, i-IM inqande ukukhula kweeseli ze-K562 nge-IC50 ye-1.03 μM. Ngokwahlukileyo, ulwalamano ...

    1011301-27-1 I-Tenovin-3 (1011301-27-1)

    I-Tenovin-3 inako ukwandisa amazinga e-P53, anqunywe kwiiseli ze-MCF-7 eziphathwe nge-6hr kwi-10 μM.Tenovin-3 ngumsebenzi we-P53 kunye ne-inhibitor ye ...

    1431866-33-9 WEHI539 (1431866-33-9)

    I-WEHI-539, inokubambisana kakhulu (subnanomolar) kunye nokukhethwa kwe-BCL-XL kwaye iyabulala ngokuthe kratya iiseli ngokuchithwa ngokukhethekileyo.