I-brake yokupaka ibhinqa ishidi lensimbi. Ukushicilela, ngokufutshane kufutshane.

Ebonisa zonke iziphumo 12

CAS NO. IGAMA LEMVELISO AMAGQABANTSHINTSHI
    1146699-66-2 Avagacestat (1146699-66-2)

    I-Avagacestat (i-BMS-708163) iyona nto inamandla, ekhethiweyo, ngomlomo engabonakaliyo γ-secretase inhibitor ye-Aβ40 kunye ne-Aβ42 ne-IC50 ye-0.3 nM ne-0.27 nM, ...

    208255-80-5 I-DAPT (GSI-IX) (208255-80-5)

    I-DAPT (i-GSI-IX) iyinombolo ye-γ-secretase inhibitor, evimbela ukuveliswa kwe-Aβ kunye ne-IC50 ye-20 nM kuma-HEK 293 amaseli.

    1446502-11-9 Enasidenib (1446502-11-9)

    I-Enasidenib ngumlomo onamandla, okhethiweyo, oguqulwayo wokuguqula i-IDH2. I-Enasidenib, i-aslo eyaziwa ngokuba ngu-AG-221 kunye neCC-90007, inamandla kwaye i ...

    313967-18-9 I-FLI-06 (313967-18-9)

    I-FLI-06 iyi-inhibitor ye-Notch yokubonakalisa nge-EC50 ye-2.3 μM. I-FLI-06 yi-Notch inhibitor kunye ne-inhibitor yangaphambili ye-secretary pathway. FL ...

    147591-46-6 ID8 (147591-46-6)

    I-ID-8 yi-DYRK inhibitor, kwaye igcina i-embryonic cell stem-self-renewal kwinkcubeko yexesha elide. I-ID-8 yi-DYRK inhibitor. I-ID-8 inokuxhasa i-Wn ...

    459168-41-3 JNJ7777120 (459168-41-3)

    I-JNJ-7777120 yinto yokuqala yokukhetha kunye ne-seleda imidazole i-histamine i-H4 receptor antagonist ne-Ki ye-4.5 nM, imibukiso> 1000-phinda ukhethe ...

    668467-91-2 I-LDN-57444 (668467-91-2)

    I-LDN-57444 i-prohibasome prohibasome inhibitor ye-Uch-L1 kunye ne-IC50 ye-0.88 μM, i-28-khetho ekhethwe phezu kwe-isoform Uch-L3.

    ...

    603139-19-1 Odanacatib (MK-0822) (603139-19-1)

    I-Odanacatib (MK 0822) yindlela enamandla, ekhethiweyo, kwaye engathathi hlangothi ye-cathepsin K (umntu / umvundla) kunye ne-IC50 ye-0.2 nM / 1 nM, kwaye ibonakalise ...

    960374-59-8 ONX0914 (PR-957) (960374-59-8)

    I-ONX-0914 (i-PR-957) iyona nto inamandla kwaye ikhetha i-immunoproteasome inhibitor ene-cross-reactivity ye-proteasome.

    ...

    847925-91-1 RO4929097 (847925-91-1)

    I-RO4929097 yi-γ secretase inhibitor ene-IC50 ye-4 nM, ukuvimbela ukusetyenziswa kwamaseli we-Aβ40 kunye ne-Notch nge-EC50 ye-14 nM ne-5 nM, inhlonipho ...

    1374598-80-7 I-TAK875 (1374598-80-7)

    I-TAK-875 yi-GPR40 i-agonist ekhethiweyo ne-EC50 ye-14 nM, i-400 idlula ngaphezulu kune-oleic acid. I-TAK-875 iyiveli, inomlomo iyatholakala, ikhetha ...

    209984-56-5 YO-01027 (Dibenzazepine) (209984-56-5)

    I-YO-01027 (Dibenzazepine) yi-dipytidic γ-secretase inhibitor ene-IC50 ye-2.6 nM kunye ne-2.9 nM kwiimvavanyo ze-cell-frees for APPL ne-Notch cleavage ...